医学
伤害
钠通道
麻醉
急性疼痛
导航1
化学
药理学
神经科学
钠
心理学
生物化学
受体
有机化学
作者
J. W. Jones,Darin Correll,Sandra Lechner,Ina Jazić,Xiaopeng Miao,David Shaw,C Simard,Jeremiah D. Osteen,Brian Hare,Alina Beaton,Todd Bertoch,Asokumar Buvanendran,Ashraf S. Habib,Lois J. Pizzi,Richard Pollak,Scott G. Weiner,Carmen Bozic,Paul A. Negulescu,Paul F. White
标识
DOI：10.1056/nejmoa2209870
摘要
The NaV1.8 voltage-gated sodium channel, expressed in peripheral nociceptive neurons, plays a role in transmitting nociceptive signals. The effect of VX-548, an oral, highly selective inhibitor of NaV1.8, on control of acute pain is being studied.
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