医学
内科学
随机对照试验
胃肠病学
癌症
临床试验
荟萃分析
肿瘤科
作者
Reza Amiri Khosroshahi,Mohammad Heidari Seyedmahalleh,Sheida Zeraattalab-Motlagh,Laleh Fakhr,Simon Wilkins,Hamed Mohammadi
标识
DOI:10.1080/01635581.2023.2274135
摘要
Until now, no study evaluated the impact of optimum intake of omega-3 fatty acids on inflammatory factors. We aimed to investigate the dose-dependent effects of omega-3 fatty acids supplementation on inflammatory factors in cancer patients. PubMed, Scopus and ISI Web of Science were searched until July 2022 to find randomized controlled trials (RCTs) for examining the efficacy of omega-3 fatty acids on inflammatory factors. Our primary outcomes were interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF-α), C-reactive protein (CRP), and albumin. The results of 33 trials (2068 participants) revealed that each 1 g/day omega-3 fatty acids (oral/enteral) significantly reduced IL-6 (SMD: -1.17 pg/ml; 95% CI: -1.78, -0.55;
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