糖组
糖组学
生物
背景(考古学)
糖生物学
寄主(生物学)
毒力
糖基化
计算生物学
功能(生物学)
细胞生物学
聚糖
遗传学
基因
糖蛋白
古生物学
作者
Rustam Aminov,Leila Aminova
出处
期刊:Glycobiology
[Oxford University Press]
日期:2023-09-23
卷期号:33 (12): 1106-1116
被引量:4
标识
DOI:10.1093/glycob/cwad073
摘要
Abstract Glycosylation plays a crucial role in many aspects of cell biology, including cellular and organismal integrity, structure-and-function of many glycosylated molecules in the cell, signal transduction, development, cancer, and in a number of diseases. Besides, at the inter-organismal level of interaction, a variety of glycosylated molecules are involved in the host-microbiota recognition and initiation of downstream signalling cascades depending on the outcomes of the glycome-mediated ascertainment. The role of glycosylation in host-microbe interactions is better elaborated within the context of virulence and pathogenicity in bacterial infection processes but the symbiotic host-microbe relationships also involve substantive glycome-mediated interactions. The works in the latter field have been reviewed to a much lesser extent, and the main aim of this mini-review is to compensate for this deficiency and summarise the role of glycomics in host-microbe symbiotic interactions.
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