入射(几何)
肺结核
疾病负担
疾病负担
人口学
置信区间
人口
环境卫生
年轻人
全球卫生
儿科
医学
公共卫生
老年学
内科学
病理
物理
护理部
社会学
光学
作者
Weijing Shang,Guiying Cao,Wenzhan Jing,Jue Liu,Wannian Liang,Min Liu
出处
期刊:Pediatrics
[American Academy of Pediatrics]
日期:2024-03-14
卷期号:153 (4)
被引量:1
标识
DOI:10.1542/peds.2023-063910
摘要
OBJECTIVE Tuberculosis (TB) is a major health threat in adolescents and young adults. However, its burden in this population remains unclear. This study aimed to assess TB burden and changing trends in individuals aged 10 to 24 years from 1990 to 2019. METHODS All data were obtained from the Global Burden of Disease Study 2019. We calculated the percentage of relative changes in incident cases, deaths, and disability-adjusted life years (DALYs). The temporal trends of the incidence, mortality, and DALYs were assessed using estimated annual percentage changes (EAPCs). RESULTS At global level, TB incidence (per 100 000 population) decreased from 144.12 in 1990 to 97.56 in 2019, with average 1.28% (95% confidence interval [CI]: 1.36%–1.19%) of decline per year. Similar decreasing trends occurred across sex, age, sociodemographic index regions, and in most Global Burden of Disease study regions and countries. TB incidence in female adolescents decreased faster than that in male. However, there was an increasing trend in the incidence of extensively drug-resistant TB (EAPC = 11.23, 95% CI: 8.22–14.33) and multidrug-resistant TB without extensive drug resistance (EAPC = 3.28, 95% CI: 1.73–4.86). South Africa had the highest increase in TB incidence (EAPC = 3.51, 95% CI: 3.11–3.92). CONCLUSIONS Global TB incidence, mortality, and DALYs in adolescents and young adults decreased from 1990 to 2019. However, the incidence of drug-resistant TB increased. TB remains a threat in adolescents and young adults worldwide, especially in low- and middle-income countries.
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