过氧化氢
活性氧
荧光
化学
荧光素
过氧化物
选择性
生物化学
氧气
生物物理学
组合化学
生物
催化作用
有机化学
量子力学
物理
作者
Kangkang Wang,Tingting Yao,Jia‐Yu Xue,Yan-qiu Guo,Xiaowei Xu
出处
期刊:Biosensors
[MDPI AG]
日期:2023-06-16
卷期号:13 (6): 658-658
被引量:7
摘要
Hydrogen peroxide (H2O2) is one of the important reactive oxygen species (ROS), which is closely related to many pathological and physiological processes in living organisms. Excessive H2O2 can lead to cancer, diabetes, cardiovascular diseases, and other diseases, so it is necessary to detect H2O2 in living cells. Since this work designed a novel fluorescent probe to detect the concentration of H2O2, the H2O2 reaction group arylboric acid was attached to the fluorescein 3-Acetyl-7-hydroxycoumarin as a specific recognition group for the selective detection of hydrogen peroxide. The experimental results show that the probe can effectively detect H2O2 with high selectivity and measure cellular ROS levels. Therefore, this novel fluorescent probe provides a potential monitoring tool for a variety of diseases caused by H2O2 excess.
科研通智能强力驱动
Strongly Powered by AbleSci AI