医学
肝细胞癌
免疫
细胞免疫
癌
癌症研究
免疫学
内科学
免疫系统
作者
Shenglu Liu,Haoxian Gou,Hui Wang,S Chen,Shaoqiu Zhuo,Mi Luo,Shu Qin,Mengyu Zhang,Jiatong Chen,Zhiwei Huang,Xianming Xia,Xiaoli Yang,Kai He
摘要
The impact of cholecystectomy, which blocks the cholecystohepatic shunt pathway (CHSP), on the prognosis of patients with hepatocellular carcinoma (HCC) is unclear. Hepatic secondary bile acids (BAs) inhibit natural killer T (NKT) cell-mediated immunity against HCC, and the regulation of homeostasis of hepatic secondary BAs is controlled by the CHSP. However, the influence of CHSP on NKT cell-mediated immunity against HCC remains unclear.
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