化学
邻苯二酚-O-甲基转移酶
甲基转移酶
儿茶酚
酶抑制剂
生物化学
酶
药理学
立体化学
甲基化
医学
等位基因
基因
作者
Sofia Benfeito,Bárbara Albuquerque,Lisa Sequeira,Carla Lima,Daniel Chavarria,Paula Serrão,Fernando Cagide,Patrício Soares‐da‐Silva,Fernanda Borges
标识
DOI:10.1021/acs.jmedchem.4c01682
摘要
A new library of non-nitrocatechol compounds (HetCAMs) was developed and their efficacy was compared to tolcapone, a standard COMT inhibitor for PD. Compound
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