(Thio)Chromenones derivatives exhibit anti-metastatic effects through selective inhibition of uPAR in cancer cell lines: Discovery of an uPAR-targeting fluorescent probe

A class of (thio)chromenone derivatives has been identified as suitable ligands for uPAR, a glycoprotein with a prognostic value in a large number of human cancers. The (thio)chromenone agents actively...