A review on advancements in the application of starch-based nanomaterials in biomedicine: Precision drug delivery and cancer therapy

生物医学 纳米技术 药物输送 纳米材料 生物相容性 癌症治疗 精密医学 计算机科学 医学 材料科学 癌症 生物信息学 生物 病理 内科学 冶金
作者
Jinjin Pei,Yuqiang Yan,Selvaraj Jayaraman,Ponnulakshmi Rajagopal,Prabhu Manickam Natarajan,Vidhya Rekha Umapathy,Sridevi Gopathy,Jeane Rebecca Roy,Janaki Coimbatore Sadagopan,Dwarakesh Thalamati,Chella Perumal Palanisamy,Monica Mironescu
出处
期刊:International Journal of Biological Macromolecules [Elsevier]
卷期号:265: 130746-130746 被引量:11
标识
DOI:10.1016/j.ijbiomac.2024.130746
摘要

The burgeoning field of starch-based nanomaterials in biomedical applications has perceived notable progressions, with a particular emphasis on their pivotal role in precision drug delivery and the inhibition of tumor growth. The complicated challenges in current biomedical research require innovative approaches for improved therapeutic outcomes, prompting an exploration into the possible of starch-based nanomaterials. The conceptualization of this review emerged from recognizing the need for a comprehensive examination of the structural attributes, versatile properties, and mechanisms underlying the efficiency of starch-based nanomaterials in inhibiting tumor growth and enabling targeted drug delivery. This review delineates the substantial growth in utilizing starch-based nanomaterials, elucidating their small size, high surface-volume ratio, and biocompatibility, predominantly emphasizing their possible to actively recognize cancer cells, deliver anticancer drugs, and combat tumors efficiently. The investigation of these nanomaterials encompasses to improving biocompatibility and targeting specific tissues, thereby contributing to the evolving landscape of precision medicine. The review accomplishes by highlighting the auspicious strategies and modern developments in the field, envisioning a future where starch-based nanomaterials play a transformative role in molecular nanomaterials, evolving biomedical sciences. The translation of these advancements into clinical applications holds the potential to revolutionize targeted drug delivery and expand therapeutic outcomes in the realm of precision medicine.
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