Brexpiprazole‐related tardive dystonia in a young patient with schizophrenia: A case report

Psychiatry and Clinical NeurosciencesEarly View Letter to the Editor Brexpiprazole-related tardive dystonia in a young patient with schizophrenia: A case report Takumi Ebina MD, Takumi Ebina MD orcid.org/0009-0001-3132-8936 Department of Psychiatry, Nagoya University Graduate School of Medicine, Nagoya, JapanSearch for more papers by this authorKunihiro Iwamoto MD, PhD, Corresponding Author Kunihiro Iwamoto MD, PhD [email protected] orcid.org/0000-0003-3868-3372 Department of Psychiatry, Nagoya University Graduate School of Medicine, Nagoya, JapanSearch for more papers by this authorMasashi Ikeda MD, PhD, Masashi Ikeda MD, PhD Department of Psychiatry, Nagoya University Graduate School of Medicine, Nagoya, JapanSearch for more papers by this author Takumi Ebina MD, Takumi Ebina MD orcid.org/0009-0001-3132-8936 Department of Psychiatry, Nagoya University Graduate School of Medicine, Nagoya, JapanSearch for more papers by this authorKunihiro Iwamoto MD, PhD, Corresponding Author Kunihiro Iwamoto MD, PhD [email protected] orcid.org/0000-0003-3868-3372 Department of Psychiatry, Nagoya University Graduate School of Medicine, Nagoya, JapanSearch for more papers by this authorMasashi Ikeda MD, PhD, Masashi Ikeda MD, PhD Department of Psychiatry, Nagoya University Graduate School of Medicine, Nagoya, JapanSearch for more papers by this author First published: 26 February 2024 https://doi.org/10.1111/pcn.13653Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat No abstract is available for this article. References 1van Harten PN, Kahn RS. Tardive dystonia. Schizophr. Bull. 1999; 25: 741–748. 10.1093/oxfordjournals.schbul.a033415 PubMedWeb of Science®Google Scholar 2Frampton JE. Brexpiprazole: A review in schizophrenia. Drugs 2019; 79: 189–200. 10.1007/s40265-019-1052-5 CASPubMedWeb of Science®Google Scholar 3Siafis S, Wu H, Wang D et al. Antipsychotic dose, dopamine D2 receptor occupancy and extrapyramidal side-effects: a systematic review and dose-response meta-analysis. Mol. Psychiatry 2023; 28: 3267–3277. 10.1038/s41380-023-02203-y CASPubMedWeb of Science®Google Scholar 4Nagai Y, Yamazaki T, Sugita T, Shibata N. Brexpiprazole-associated Pisa syndrome (Pleurothotonus) in a patient with dementia. Clin. Neuropharmacol. 2022; 45: 72–73. 10.1097/WNF.0000000000000500 PubMedGoogle Scholar 5Adityanjee AYA, Jampala VC, Mathews T. The current status of tardive dystonia. Biol. Psychiatry 1999; 45: 715–730. 10.1016/S0006-3223(98)00242-X CASPubMedWeb of Science®Google Scholar 6Quartarone A, Hallett M. Emerging concepts in the physiological basis of dystonia. Mov. Disord. 2013; 28: 958–967. 10.1002/mds.25532 CASPubMedWeb of Science®Google Scholar 7Wallman MJ, Gagnon D, Parent M. Serotonin innervation of human basal ganglia. Eur. J. Neurosci. 2011; 33: 1519–1532. 10.1111/j.1460-9568.2011.07621.x PubMedWeb of Science®Google Scholar 8Wieland S, Lucki I. Altered behavioral responses mediated by serotonin receptors in the genetically dystonic (dt) rat. Brain Res. Bull. 1991; 26: 11–16. 10.1016/0361-9230(91)90185-M CASPubMedGoogle Scholar 9Yada Y, Kitagawa K, Sakamoto S et al. The relationship between plasma clozapine concentration and clinical outcome: A cross-sectional study. Acta Psychiatr. Scand. 2021; 143: 227–237. 10.1111/acps.13264 CASPubMedWeb of Science®Google Scholar Early ViewOnline Version of Record before inclusion in an issue ReferencesRelatedInformation