少牙症
少汗性外胚层发育不良
医学
检查表
系统回顾
牙齿异常
梅德林
外胚层发育不良
皮肤病科
牙科
心理学
生物
生物化学
认知心理学
作者
Natália Lopes Castilho,Kêmelly Karolliny Moreira Resende,Juliana Amorim dos Santos,Renato Assis Machado,Ricardo D. Coletta,Eliete Neves Silva Guerra,Ana Carolina Acevedo,Hercílio Martelli‐Júnior
摘要
The aim of this systematic review was to describe the clinical and genetic features of syndromes showing oligodontia as a sign. The review was performed according to the PRISMA 2020 checklist guidelines, and the search was conducted using PubMed, Scopus, Lilacs, Web of science, Livivo, and EMBASE and supplemented by a gray literature search on Google Scholar and ProQuest, applying key terms relevant to the research questions. The systematic review identified 47 types of syndromes in 83 studies, and the most common was hypohidrotic ectodermal dysplasia, which was reported in 24 patients in 22 studies. Other common syndromes that reported oligodontia included Axenfeld–Rieger syndrome, Witkop’s syndrome, Ellis–van Creveld syndrome, blepharocheilodontic syndrome, and oculofaciocardiodental syndrome. The X-linked mode of inheritance was the most reported (n = 13 studies), followed by the autosomal dominant (n = 13 studies). The review describes the main syndromes that may have oligodontia as a clinical sign and reinforces the need for orodental–facial examining for adequate diagnosis and treatment of the affected patients. Molecular analysis in order to better understand the occurrence of oligodontia is imperative.
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