超分子化学
超分子手性
拉曼光学活性
背景(考古学)
纤维
淀粉样纤维
手性(物理)
纳米技术
拉曼光谱
圆二色性
淀粉样蛋白(真菌学)
化学
材料科学
结晶学
淀粉样β
物理
晶体结构
光学
生物化学
生物
病理
无机化学
医学
疾病
手征对称破缺
夸克
古生物学
量子力学
Nambu–Jona Lasinio模型
作者
Zuzanna Majka,Karolina Kwiecień,Agnieszka Kaczor
标识
DOI:10.1002/cplu.202400091
摘要
Abstract Amyloid fibrils are supramolecular systems showing distinct chirality at different levels of their complex multilayered architectures. Due to the regular long‐range chiral organization, amyloid fibrils exhibit the most intense Vibrational Optical Activity (VOA) signal observed up to now, making VOA techniques: Vibrational Circular Dichroism (VCD) and Raman Optical Activity (ROA) very promising tools to explore their structures, handedness and intricate polymorphism. This concept article reviews up‐to‐date experimental studies on VOA applications to investigate amyloid fibrils highlighting its future potential in analyzing of these unique supramolecular systems, in particular in the context of biomedicine and nanotechnology.
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