PVT1型
乳腺癌
医学
转移
癌症
治疗方法
肿瘤科
癌症研究
疾病
内科学
生物
长非编码RNA
下调和上调
遗传学
基因
作者
Kamilya Jamel Baljon,Pushpamala Ramaiah,Ebraheem Abdu Musad Saleh,F. Al-dolaimy,Farqad Hassan Al-Dami,Kumaraswamy Gandla,Adnan Taan Alkhafaji,Ahmed hussien R. Abbas,Ali Hashiem Alsaalamy,Yashwant Singh Bisht
标识
DOI:10.1016/j.prp.2023.154675
摘要
A significant number of women are identified with breast cancer (BC) every year, making it among the most prevalent malignancies and one of the leading causes of mortality globally. Despite significant progress in understanding BC pathogenesis and treatment options, there is still a need to identify new therapeutic targets and develop more effective treatments. LncRNAs have been discovered as biomarkers and a promising target for various cancers, including BC. PVT1 is a particular one of these lncRNAs, and research has indicated that it has a significant impact on the appearance and progression of BC.PVT1 is an attractive therapeutic target for BC due to its role in promoting cancer cell growth, metastasis and invasion. In addition to its potential as a treatment strategy, PVT1 may also have diagnostic value in BC. In this article, we will discuss targeting PVT1 as a treatment strategy for BC.
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