Study of Rhodamine‐Based Fluorescent Probes for Organic Radical Intermediates

Abstract Rhodamine‐based amide derivatives for the detection of radical intermediates in organic reactions were synthesized and used as fluorescent probes over a wide range of solvents. The mechanistic studies confirm a reversible opening and closing of the spirolactam ring. Compound 21 can be used to support the radical mechanism or in the real‐time monitoring of radical intermediates.