Coagulopathy in traumatic brain injury

We read with great interest the recent article by Lustenberger et al. on the time course of coagulopathy after isolated traumatic brain injury (TBI) and its relationship to in-hospital outcomes. In this retrospective study the authors found that 45.7% of patients developed coagulopathy after severe TBI. The coagulopathy can occur up to 5 days after admission with a prolonged duration in 30% of patients. Patients with early coagulopathy were associated with increased morbidity and poor outcomes. 2 Lustenberger T. Talving P. Kobayashi L. et al. Time course of coagulopathy in isolated severe traumatic brain injury. Injury. 2011; 42: 114 PubMed Google Scholar