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Postimatinib therapy emergence of a new JAK2V617F clone and subsequent development of overt polycythemia vera in a patient with chronic myelogenous leukaemia

医学 血液学 癌症遗传学 内科学 家庭医学 癌症
作者
Ayalew Tefferi,Ralph Levitt,Terra L. Lasho,Ryan A. Knudson,Rhett P. Ketterling
出处
期刊:European Journal of Haematology [Wiley]
卷期号:85 (1): 86-87 被引量:14
标识
DOI:10.1111/j.1600-0609.2010.01458.x
摘要

European Journal of HaematologyVolume 85, Issue 1 p. 86-87 Postimatinib therapy emergence of a new JAK2V617F clone and subsequent development of overt polycythemia vera in a patient with chronic myelogenous leukaemia Ayalew Tefferi, Ayalew Tefferi 1Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MNSearch for more papers by this authorRalph Levitt, Ralph Levitt 2MeritCare Roger Maris Cancer Center, Fargo, NDSearch for more papers by this authorTerra L. Lasho, Terra L. Lasho 1Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MNSearch for more papers by this authorRyan A. Knudson, Ryan A. Knudson 3Division of Cytogenetics, Department of Laboratory Medicine, Mayo Clinic, Rochester, MN, USASearch for more papers by this authorRhett P. Ketterling, Rhett P. Ketterling 3Division of Cytogenetics, Department of Laboratory Medicine, Mayo Clinic, Rochester, MN, USASearch for more papers by this author Ayalew Tefferi, Ayalew Tefferi 1Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MNSearch for more papers by this authorRalph Levitt, Ralph Levitt 2MeritCare Roger Maris Cancer Center, Fargo, NDSearch for more papers by this authorTerra L. Lasho, Terra L. Lasho 1Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MNSearch for more papers by this authorRyan A. Knudson, Ryan A. Knudson 3Division of Cytogenetics, Department of Laboratory Medicine, Mayo Clinic, Rochester, MN, USASearch for more papers by this authorRhett P. Ketterling, Rhett P. Ketterling 3Division of Cytogenetics, Department of Laboratory Medicine, Mayo Clinic, Rochester, MN, USASearch for more papers by this author First published: 15 June 2010 https://doi.org/10.1111/j.1600-0609.2010.01458.xCitations: 1 Ayalew Tefferi, MD, Mayo Clinic, Rochester MN 55905, USA. Tel: +1 507 284 3159; Fax: +1 507 266 4972; e-mail: [email protected] Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat No abstract is available for this article. References 1 Bee PC, Gan GG, Nadarajan VS, Latiff NA, Menaka N. A man with concomitant polycythaemia vera and chronic myeloid leukemia: the dynamics of the two disorders. Int J Hematol 2010; 91: 136–9. 10.1007/s12185-009-0471-6 PubMedWeb of Science®Google Scholar 2 Bocchia M, Vannucchi AM, Gozzetti A, Guglielmelli P, Poli G, Crupi R, Defina, M, Bosi, A, Francesco, L. Insights into JAK2-V617F mutation in CML. Lancet Oncol 2007; 8: 864–6. 10.1016/S1470-2045(07)70295-4 CASPubMedWeb of Science®Google Scholar 3 Pingali SR, Mathiason MA, Lovrich SD, Go RS. Emergence of chronic myelogenous leukemia from a background of myeloproliferative disorder: JAK2V617F as a potential risk factor for BCR-ABL translocation. Clin Lymphoma Myeloma 2009; 9: E25–9. 10.3816/CLM.2009.n.080 PubMedWeb of Science®Google Scholar 4 Mirza I, Frantz C, Clarke G, Voth AJ, Turner R. Transformation of polycythemia vera to chronic myelogenous leukemia. Arch Pathol Lab Med 2007; 131: 1719–24. 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Classification and diagnosis of myeloproliferative neoplasms: the 2008 World Health Organization criteria and point-of-care diagnostic algorithms. Leukemia 2008; 22: 14–22. 10.1038/sj.leu.2404955 CASPubMedWeb of Science®Google Scholar 15 Tefferi A, Vardiman JW. Myelodysplastic syndromes. N Engl J Med 2009; 361: 1872–85. 10.1056/NEJMra0902908 CASPubMedWeb of Science®Google Scholar 16 Tefferi A, Lasho TL, Patnaik MM, Finke CM, Hussein K, Hogan WJ, Elliott MA, Litzow MR, Hanson CA, Pardanani A. JAK2 germline genetic variation affects disease susceptibility in primary myelofibrosis regardless of V617F mutational status: nullizygosity for the JAK2 46/1 haplotype is associated with inferior survival. Leukemia 2010; 24: 105–9. 10.1038/leu.2009.225 CASPubMedWeb of Science®Google Scholar 17 Pardanani A, Lasho TL, Finke CM, Gangat N, Wolanskyj AP, Hanson CA, Tefferi A. 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