复印件
复印机
高尔基体
内质网
小泡
生物
细胞生物学
分泌途径
转运蛋白
分泌蛋白
囊泡转运蛋白
布雷菲尔德A
蛋白质靶向
膜泡运输蛋白质类
分泌物
内体
膜蛋白
生物化学
膜
液泡蛋白分选
细胞内
作者
Walter Nickel,Britta Brügger,Felix Wieland
标识
DOI:10.1006/scdb.1998.0256
摘要
Vesicular traffic within the early secretory pathway is mediated by COPI- and COPII-coated vesicles. While COPII-coated vesicles appear to be involved exclusively in the export of secretory proteins and lipids from the endoplasmic reticulum (ER), COPI-coated vesicles seem to function in both anterograde and retrograde transport between the ER-Golgi intermediate compartment (IC) and the Golgi as well as in intra-Golgi transport. Here, we focus on (i) the mechanisms how these transport carriers are formed from a given donor membrane; and (ii) the possible mechanisms involved in sorting of proteins and lipids into such transport vesicles.
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