蛆虫
清创术(牙科)
医学
外科
体内
生物
植物
生物技术
作者
Pascal Steenvoorde,Cathrien Jacobi,Jacques Oskam
出处
期刊:Advances in Skin & Wound Care
[Ovid Technologies (Wolters Kluwer)]
日期:2005-10-01
卷期号:18 (8): 430-435
被引量:44
标识
DOI:10.1097/00129334-200510000-00010
摘要
To determine which method of maggot debridement therapy--free-range or contained--is more effective for wound healing.In vivo study of 64 patients with 69 chronic wounds that showed signs of gangrenous or necrotic tissue. Patients were treated with either free-range or contained maggot debridement therapy according to maggot availability, dressing difficulty, and physician preference.Significantly better outcomes were achieved with the free-range technique versus the contained technique (P = .028). With the free-range technique, the mean number of maggot applications and the total number of maggots per treatment were significantly lower than with the contained application technique (P = .028 and P < .001, respectively).This clinical in vivo study supports in vitro studies in which containment of maggots was found to reduce the effectiveness of maggot debridement therapy.
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