免疫疗法
癌症
癌症免疫疗法
医学
免疫系统
免疫逃逸
肿瘤微环境
免疫检查点
免疫学
癌症研究
抗原
免疫监视
彭布罗利珠单抗
获得性免疫系统
内科学
作者
Gregory L. Beatty,Whitney L. Gladney
标识
DOI:10.1158/1078-0432.ccr-14-1860
摘要
Immunotherapy has demonstrated impressive outcomes for some patients with cancer. However, selecting patients who are most likely to respond to immunotherapy remains a clinical challenge. Here, we discuss immune escape mechanisms exploited by cancer and present strategies for applying this knowledge to improving the efficacy of cancer immunotherapy.
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