The nature and mechanism of incisional wound healing has been and continues to be of interest to clinicians and wound biologists. More than 46 million operations are performed in the United States alone each year (1). To shorten the time required for incisional wound healing is not only relevant to reducing postoperative pain and impairment as well as convalescence but is also cost-effective. It is very important to understand the nature, the mechanism, and the process of incisional wound healing before designing an experiment.