[Reactive oxygen species in pathogenesis of central nervous system diseases].

Many recent studies have provided evidence that reactive oxygen species (ROS) and other free radicals are implicated in pathogenesis of various central nervous system (CNS) diseases. In this paper the formation of ROS, protective mechanisms, nonenzymatic and enzymatic antioxidative markers are presented as well as the role of ROS and oxidative stress in CNS diseases in children and in adult patients.