细胞凋亡
流式细胞术
淋巴细胞
生物
T淋巴细胞
细胞生物学
分子生物学
免疫学
生物化学
体外
作者
Peihong Chen,Zongbao Ding,Yang Xie,Tong Li
出处
期刊:PubMed
日期:2011-08-01
卷期号:34 (8): 1237-41
摘要
To screen the activated fraction from Celastrus aculeatus and study its effect on T lymphocyte apoptosis.Different polarity fractions were isolated from Celastrus aculeatus extract. Flow Cytometry method was used to detect apoptosis ratio of the active fractions.Different fractions extract from Celastrus aculeatus and GSF-A could significantly inhibit T lymphocyte proliferation and induce T lymphocyte apoptosis.The activated fractions isolated from Celastrus aculeatus have anti-inflammatory effect. Its mechanism may be related to the apoptosis effect on T lymphocyte.
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