液体活检
微流控
恶性肿瘤
癌症
纳米技术
微流控芯片
药物输送
疾病
癌症治疗
计算机科学
医学
重症监护医学
材料科学
病理
内科学
作者
Ana C Q Silva,Carla Vilela,Hélder A. Santos,Armando J. D. Silvestre,Carmen S.R. Freire
标识
DOI:10.1016/j.apmt.2019.100450
摘要
Cancer is the second leading cause of non-accidental death in the world, accounting for roughly 9.6 million deaths in 2018. In the latter years, research in this domain has grown exponentially, as a way to provide deep insights into this malignancy, but also new tools for early diagnosis and efficient personalized treatment options. Microfluidic lab-on-a-chip technology has demonstrated a high potential on the design of new methodologies for cancer diagnosis, treatment and disease follow-up. Here, we present a detailed review on the application of the microfluidic platforms for the detection and separation of tumour cells from blood (liquid biopsy) and the development of new drug delivery systems for cancer conquering.
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