Relationship between TPOAb, TGAb and female infertility

Objective To explore the relationship between thyroid peroxidase antibody (TPOAb), thyroglobulin antibody (TGAb) and female infertility. Methods Serum levels of ATA, including TPOAb and TGAb, were detected with electrochemiluminescence method in 543 infertile women (infertility group) and 100 healthy women (control group), and the positive rates of the two groups were compared. Results The positive rate of TPOAb in infertility group was higher than that in control group (19.2% vs.9.0%; χ2=6.009 42, P 0.05). The positive rate of ATA in infertility group was higher than that in control group (24.1% vs.15.0%; χ2=4.006 72, P<0.05). Conclusion TPOAb and TGAb are closely related to female infertility, and the joint detection is helpful to the cause lookup of female infertility. Key words: Thyroid peroxidase antibody (TPOAb); Thyroglobulin antibody (TGAb); Female infertility