特应性皮炎
斯科拉德
医学
皮肤科生活质量指数
湿疹面积及严重程度指数
患者报告的结果
生活质量(医疗保健)
疾病严重程度
皮肤病科
物理疗法
内科学
护理部
银屑病
作者
Jonathan I. Silverberg,Donald Lei,Muhammad Yousaf,Sherief R. Janmohamed,Paras P. Vakharia,R. Chopra,Rajeev Chavda,Sylvie Gabriel,Kevin R. Patel,Vivek Singam,Robert Kantor,Derek Y. Hsu
标识
DOI:10.1016/j.anai.2020.03.006
摘要
Background Little is known about the measurement properties of Patient-Oriented Scoring Atopic Dermatitis (PO-SCORAD) in adults with atopic dermatitis (AD). Even less is known about how PO-SCORAD performs compared with the Patient-Oriented Eczema Measure (POEM). Objective To examine the measurement properties of PO-SCORAD and compare them with those of POEM. Methods A prospective dermatology practice–based study of 291 patients with AD (age range, 18-72 years). Results PO-SCORAD and POEM were moderately correlated with each other (Spearman ρ = 0.56) and had weak-moderate correlations with the Numeric Rating Scale (NRS) worst itch and average itch, Dermatology Life Quality Index (DLQI), ItchyQOL, Patient-Reported Outcomes Measurement Information System (PROMIS) Sleep Disturbance (SD) and Sleep-Related Impairment (SRI), Patient Health Questionnaire-9 (PHQ-9), and Eczema Area and Severity Index (EASI) (P < .001). POEM had significantly stronger correlations with DLQI, ItchyQOL, and EASI than did PO-SCORAD. PO-SCORAD and POEM had fair discriminant validity. Changes from baseline in PO-SCORAD and POEM were moderately correlated with each other; were weakly to strongly correlated with NRS worst itch and average itch, DLQI, ItchyQOL, PROMIS SD, PROMIS SRI, PHQ-9, and EASI; and had good test-retest reliability. There was no differential item functioning of items or floor or ceiling effects for PO-SCORAD or POEM. The thresholds for meaningful change for PO-SCORAD and POEM were −15.5 and −5.0, respectively. Median completion times for PO-SCORAD and POEM were 3 minutes and 1 minute, respectively. Conclusion PO-SCORAD and POEM had good construct and cross-cultural validity, reliability, and responsiveness in adults with AD and were feasible for use in clinical trials and practice. However, POEM had better measurement properties than PO-SCORAD.
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