Fuzzy reference data estimation in brain tumor segmentation studies

The evaluation process involves the design of a reliable common agreement strategy able to define a suitable reference standard by taking a combination of expert segmentations.Strategies for combination of multiple segmentations, also mentioned as label fusion, have recently been introduced as effective methods to obtain segmentations that are more accurate than any of the individual input segmentations. (Warfield et al. 2004),(Bouix et al. 2007),(Rohlfing and Jr. 2007),(Robitaille and Duchesne 2012).