Ocular Nanomedicine In article number 2003699, Zhimin Tang, Xianqun Fan, Yu Chen, and Ping Gu comprehensively overview the distinctive functional ocular nanomedicine as potential alternatives for multipurpose ocular applications. By affording insight into challenges encountered by ocular nanomedicine and further highlighting the direction of future studies, this review provides an incentive for enriching ocular nanomedicine-based fundamental research and future clinical translation.