磁共振成像
材料科学
钆
对比度(视觉)
纳米颗粒
锰
纳米结构
核磁共振
毒性
氧化锰
氧化物
纳米技术
对比度增强
计算机科学
化学
放射科
物理
医学
人工智能
冶金
有机化学
作者
Shabnam Hashemzadeh,Mohamad Esmaeil Akbari,Seyed Amin Astani,Jaber Hashemzadeh,Asghar Ashrafi Hafez
出处
期刊:NANO
[World Scientific]
日期:2022-02-01
卷期号:17 (02)
被引量:2
标识
DOI:10.1142/s1793292022300031
摘要
Magnetic resonance imaging (MRI) is a noninvasive, imaging technique of soft tissues, providing the possibility for three-dimensional, high temporal and spatial resolution imaging. Gadolinium complexes are the most frequently used [Formula: see text]-weighted contrast agents (CAs) to enhance the signal intensity of images. The toxicity of released Gd[Formula: see text] has shifted the attention of researchers to manganese (Mn) oxide nanoparticles (NPs) as a [Formula: see text]-weighted CA. Different phases and shapes of Mn oxide nanostructures with various coatings have been investigated to achieve the highest efficacy and lowest toxicity. In this review, engineering effects of Mn oxide nanostructures on image quality, toxicity and targeting have been studied. Switchable, multimodal imaging and theranostic systems, based on Mn oxide nanostructures, were also reviewed.
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