Bisphenol A

The word estrogen is commonly used to refer to 17b-estradiol (E2) due to its physiological relevance and predominance during reproductive growth.Estrogens are sex steroid hormones primarily synthesized in the ovaries and the adrenal glands, adipose tissue, brain, and testis.Estrogen displays a broad spectrum of physiological functions, including regulation of the menstrual cycle and reproduction, bone density, brain function, cholesterol mobilization, control of inflammation, and development of breast tissue and sexual organs. 1 While estrogens play diverse and similar physiological roles in both sexes, 2 they control primary and secondary sexual characteristics in females.3][4][5] The lower levels of estrogens produced in men are essential for sperm maturation, erectile function, and healthy libido. 6Besides this sexual and reproductive role, E2 exerts many actions in other systems such as the adipose tissue, bone, brain, Issues in Toxicology No.