材料科学
光子上转换
涂层
配体(生物化学)
发光
壳体(结构)
荧光
介孔材料
光电子学
纳米技术
化学
纳米颗粒
光学
复合材料
催化作用
有机化学
生物化学
受体
物理
作者
E. Pavitra,Hoomin Lee,Seung Kyu Hwang,Jin Young Park,Ganji Lakshmi Varaprasad,Mandava V. Basaveswara Rao,Young‐Kyu Han,G. Seeta Rama Raju,Yun Suk Huh
标识
DOI:10.1016/j.apsusc.2021.152166
摘要
Over past decades, evolutions in health care and breakthroughs in medicine have remarkably enriched the quality of life. Recently, it was realized that multifunctional nanoparticles offer an efficient means of addressing many challenges faced by those developing various biomedical applications. Herein, we report large-pore mesoporous silica (LPMS) coated AgGd(MoO4)2:2Er3+/10Yb3+ (AGM:Er3+/Yb3+@mSi) upconversion nanoplates for the first time. After coating AGM:Er3+/Yb3+ nanoplates with LPMS shell, the specific surface area increased from 17.19 to 128.25 m2/g. Under 980 nm laser excitation, upconversion emission intensity was enhanced 2.71-fold due to the existence of cooperative ligand fields at the interface of AGM nanoplate and LPMS shell. Based on the luminescence intensity ratio of thermally combined excited states of Er3+ ions (2H11/2/4S3/2), the temperature sensing performance of AGM:Er3+/Yb3+@mSi core–shell nanoplates was estimated to be ∼ 0.0152 K−1 at 473 k. Cytocompatibility studies revealed the non-toxic natures of AGM:Er3+/Yb3+ and AGM:Er3+/Yb3+@mSi core–shell nanoplates, and in vitro fluorescence studies confirmed their internalization and wide distribution in HeLa cells. Furthermore, drug loading and releasing efficiencies suggested their potential use as multifunctional materials for detecting and targeting cancer and cancer-associated molecules.
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