Ozone pre-oxidation can effectively degrade MC-LR, 2mg / L ozone for MC-LR removal efficiency of 65.28%.2mg / L ozone for MC-LR removal efficiency reach to 65.28%.Ozone also has a better removal effect for turbidity and UV 254 , 4mg / L ozone for UV 254 and turbidity removal efficiency are 50% and 59.38%.But ozone removal efficiency of TOC and COD Mn was poor, 3mg / L ozone for TOC and COD Mn removal rate are only 15.06% and 14.29%.