黄斑病
光学相干断层摄影术
脉络膜新生血管
年龄相关性黄斑病变
脉络膜
萎缩
新生血管
光学相干层析成像
眼科
医学
黄斑变性
视网膜
视网膜病变
内科学
光学
血管生成
物理
糖尿病
内分泌学
作者
Yanbing Wang,Chengyan Jiang,Xiujuan Zhao,Jing Chen,Jun Li,Xia Huang,Bingqian Liu,Lin Lü
出处
期刊:Retina-the Journal of Retinal and Vitreous Diseases
[Ovid Technologies (Wolters Kluwer)]
日期:2021-12-30
卷期号:42 (4): 679-688
被引量:7
标识
DOI:10.1097/iae.0000000000003397
摘要
To assess changes in myopic maculopathy based on the ATN classification system with optical coherence tomography angiography.This was a cross-sectional study. The macular choroidal thickness (MCT) and the choriocapillaris flow (CC) were measured with optical coherence tomography angiography. The relationship of MCT and CC with different chorioretinal atrophy (A), myopic foveoschisis (T), and myopic neovascularization (N) grades was investigated.One hundred and fifty-three participates (219 eyes) were included. MCT and CC had no significant correlation with different T grades (P > 0.05). Choriocapillaris flow had a significant decrease in eyes with lacquer cracks compared with those with no neovascular maculopathy (P < 0.05) and showed a significant increase in active choroidal neovascularization compared with those with lacquer cracks (P < 0.05). Macular choroidal thickness and CC had negative correlations with different A grades (P < 0.001). MCT showed the greatest decrease in the early stage of myopic atrophic maculopathy (P < 0.001), and CC showed the most significant reduction in the late stage (P < 0.001).Choroidal changes in the highly myopic patients were detected by optical coherence tomography angiography. Progressive ischemia in the macula may play an important role in the development of myopic atrophic maculopathy. Active choroidal neovascularization may have manifested as compensation for the decrease in MCT and CC. On the contrary, myopic traction maculopathy had little correlation with choroidal changes.
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