纳米棒
选择性
萃取(化学)
分子印迹
单体
卵清蛋白
表面改性
色谱法
化学
化学工程
材料科学
糖蛋白
纳米技术
生物化学
聚合物
有机化学
生物
抗原
遗传学
工程类
物理化学
催化作用
作者
Zhiyang Guo,Yi Sun,Lirui Zhang,Qian Ding,Wei Chen,Hao Yu,Qingyun Liu,Min Fu
标识
DOI:10.1016/j.jcis.2022.02.019
摘要
In this paper, combining phenylboronic affinity, surface imprinting, and magnetic Fe3O4, a novel surface imprinted core-shell nanorod (Fe3O4@SiO2/MIPs) was developed for glycoprotein extraction. The Fe3O4@SiO2/MIPs was prepared in water solution using dopamine as functional monomer. The Fe3O4@SiO2/MIPs showed high binding capacity (175.2 mg/g) and fast mass transfer rate (40 min) toward the template protein (ovalbumin, OVA). In addition, the successful extraction of OVA from egg white confirmed the outstanding selectivity of the obtained material. All these results demonstrated that the Fe3O4@SiO2/MIPs had broad application prospects in glycoprotein recognition, biomedical research and clinical diagnosis.
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