银屑病
医学
肥胖
银屑病性关节炎
超重
代谢综合征
疾病
风险因素
皮肤病科
发病机制
内科学
作者
Peter Jensen,Lone Skov
出处
期刊:Dermatology
[S. Karger AG]
日期:2016-01-01
卷期号:232 (6): 633-639
被引量:201
摘要
Psoriasis is a common chronic inflammatory skin disease with a complex pathogenesis consisting of a genetic component, immune dysfunction, and environmental factors. It is associated with numerous comorbidities including psoriatic arthritis, cardiovascular disease, metabolic syndrome, and obesity. Evidence suggests that obesity is a risk factor for incident psoriasis, aggravates existing psoriasis, and that weight reduction may improve the severity of psoriasis in overweight individuals. Excess body weight may interfere with the medical treatment used in psoriasis and adds to the cardiovascular risk profile in these patients, which underscores the importance of effective weight control regimens. In this review we examine the current literature with regard to the association between obesity and psoriasis.
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