Expanded allogeneic stem cells (Cx601) for complex perianal fistulas in Crohn’s disease: a phase 3 randomised, double-blinded controlled trial

Background Complex perianal fistulas in Crohn’s disease are challenging to treat. Allogeneic, expanded, adipose-derived stem cells (Cx601) are a promising new therapeutic approach. We aimed to assess the safety and efficacy of Cx601 for treatment-refractory complex perianal fistulas in patients with Crohn’s disease.