Patient-Doctor Contact Interval and Clinical Outcomes in Continuous Ambulatory Peritoneal Dialysis Patients

医学 腹膜透析 连续不卧床腹膜透析 回廊的 透析 重症监护医学 外科 内科学
作者
Chunyan Yi,Qunying Guo,Jianxiong Lin,Jianying Li,Xueqing Yu,Xiao Yang
出处
期刊:American Journal of Nephrology [Karger Publishers]
卷期号:45 (4): 346-352 被引量:9
标识
DOI:10.1159/000464258
摘要

<b><i>Background:</i></b> The optimal patient-doctor contact (PDC) interval remains unknown in peritoneal dialysis (PD) patients. The aim was to investigate the association between PDC interval and clinical outcomes in continuous ambulatory PD (CAPD) patients. <b><i>Methods:</i></b> In this retrospective cohort study, CAPD patients who resided in Guangzhou city between January 2006 and December 2012 were included. According to receiver operating characteristic curve analysis, all patients were classified as high (PDC interval ≤2 months) and low (PDC interval >2 months) PDC frequency groups. Biochemical data, clinical events, and clinical outcomes during the follow-up period were compared. <b><i>Results:</i></b> Of 433 CAPD patients, the mean age was 51.3 ± 15.7 years, 54.3% of patients were male, and 29.1% with diabetes. The median vintage of PD was 45.8 (26.3-69.1) months. Patients with high PDC frequency (<i>n</i> = 233) had better patient-survival rates (99.6, 87.7, and 76.5% vs. 92.7, 76.5, and 58.7% at 1, 3, and 5 years; <i>p</i> < 0.001), lower peritonitis rate (0.17 vs. 0.23 episodes per patient-year; <i>p</i> < 0.001), and hospitalization rate (0.49 vs. 0.67 episodes per patient-year; <i>p</i> < 0.001) than those in the low PDC frequency group (<i>n</i> = 200). After adjustment for confounders, PDC interval of no more than 2 months was independently associated with better patient survival (hazard ratio 0.60, 95% CI 0.42-0.86, <i>p</i> = 0.006). <b><i>Conclusion:</i></b> A PDC interval of 2 months or less was associated with better clinical outcomes in CAPD patients. This indicates that a shorter PDC interval should be encouraged for them to achieve better clinical outcomes.
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