Personalised treatment plan for children and adolescents with advanced haematological malignancies: a response to paediatric relapsed acute leukaemia: curative intent chemotherapy improves quality of life

Research focusing on quality of life (QoL) in children and adolescents with high-risk malignancy (HRM) is of primary importance. As most of these patients are treated in low-income and middle-income countries,1 publications from Central America are of great value. We are thankful to Salaverria et al . for their work addressing this complex and key subject.2 Patients with HRM were defined by Mahmood et al. as having >50% risk of death due to their disease. These patients should receive optimal symptom management and optimal disease-directed therapies to increase both their survival and QoL. To …