Asymmetric palladium catalysed allylic substitution using phosphorus containing oxazoline ligands

A series of new phosphorus-containing oxazoline ligands has been developed. The use of these ligands for asymmetric palladium catalysed allylic substitution of 1,3-diphenylprop-2-enyl-1-acetate 12 with the sodium salt of dimethylmalonate has been achieved with 90 – 94% ee and 88 – 99% yield.