[HIV/AIDS related frailty syndrome in the elderly and related research progress].

Frailty syndrome, caused by degenerative changes in the body and the body vulnerability due to a variety of chronic diseases, is associated with adverse outcomes, such as fall, disability and mortality. With the development of antiretroviral therapy, the average life span of HIV/AIDS patients is extended, the number of elderly living with HIV/AIDS has increased, resulting the increase of the incidence of frailty syndrome in this population. The incidence of frailty syndrome in the elderly is associated with HIV infection and adverse reaction of antiretroviral therapy. Early assessment and intervention of frailty syndrome in elderly HIV/AIDS patients can reduce adverse clinical events and improve the quality of life.衰弱综合征是由机体退行性改变和多种慢性疾病引起的机体易损性增加的综合征，与跌倒、残疾和死亡等不良结局密切相关。随着抗病毒治疗的开展，艾滋病患者的平均生存期限逐渐延长，老年HIV/AIDS人数增加，衰弱综合征在该人群中的患病率增加。老年衰弱综合征的发生与HIV感染及抗病毒治疗药物的不良反应有关。早期识别与干预老年HIV/AIDS的衰弱综合征可以减少不良临床事件，提高其生存质量。.