Electrocardiographic predictors of successful resynchronization of left bundle branch block by His bundle pacing

左束支阻滞 医学 心脏再同步化治疗 心脏病学 内科学 心力衰竭 束支阻滞 置信区间 优势比 心电图 射血分数
作者
Ahran Arnold,Matthew Shun‐Shin,Daniel Keene,James P. Howard,Ji‐Jian Chow,Elaine Lim,Smaragda Lampridou,Alejandra Andrea Miyazawa,Amal Muthumala,Mark Tanner,Norman Qureshi,David Lefroy,Michael Koa‐Wing,Nick Linton,Phang Boon Lim,Nicholas S. Peters,Prapa Kanagaratnam,Angelo Auricchio,Dárrel P. Francis,Zachary I. Whinnett
出处
期刊:Journal of Cardiovascular Electrophysiology [Wiley]
卷期号:32 (2): 428-438 被引量:9
标识
DOI:10.1111/jce.14845
摘要

Abstract Background His bundle pacing (HBP) is an alternative to biventricular pacing (BVP) for delivering cardiac resynchronization therapy (CRT) in patients with heart failure and left bundle branch block (LBBB). It is not known whether ventricular activation times and patterns achieved by HBP are equivalent to intact conduction systems and not all patients with LBBB are resynchronized by HBP. Objective To compare activation times and patterns of His‐CRT with BVP‐CRT, LBBB and intact conduction systems. Methods In patients with LBBB, noninvasive epicardial mapping (ECG imaging) was performed during BVP and temporary HBP. Intrinsic activation was mapped in all subjects. Left ventricular activation times (LVAT) were measured and epicardial propagation mapping (EPM) was performed, to visualize epicardial wavefronts. Normal activation pattern and a normal LVAT range were determined from normal subjects. Results Forty‐five patients were included, 24 with LBBB and LV impairment, and 21 with normal 12‐lead ECG and LV function. In 87.5% of patients with LBBB, His‐CRT successfully shortened LVAT by ≥10 ms. In 33.3%, His‐CRT resulted in complete ventricular resynchronization, with activation times and patterns indistinguishable from normal subjects. EPM identified propagation discontinuity artifacts in 83% of patients with LBBB. This was the best predictor of whether successful resynchronization was achieved by HBP (logarithmic odds ratio, 2.19; 95% confidence interval, 0.07–4.31; p = .04). Conclusion Noninvasive electrocardiographic mapping appears to identify patients whose LBBB can be resynchronized by HBP. In contrast to BVP, His‐CRT may deliver the maximum potential ventricular resynchronization, returning activation times, and patterns to those seen in normal hearts.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
火星上凌瑶完成签到,获得积分10
1秒前
高木森完成签到,获得积分10
1秒前
zhengpaipian完成签到,获得积分10
1秒前
大胆的衬衫完成签到,获得积分10
2秒前
pluto应助科研鸟采纳,获得10
2秒前
李子完成签到,获得积分10
2秒前
迷人的冰蓝完成签到,获得积分10
3秒前
YFovY完成签到,获得积分10
3秒前
yemma应助超帅的芷蕾采纳,获得10
3秒前
一一发布了新的文献求助10
4秒前
哈罗完成签到,获得积分10
4秒前
SYLH应助111采纳,获得10
4秒前
李爱国应助Felix采纳,获得10
5秒前
vv完成签到,获得积分10
6秒前
任性的初蝶完成签到 ,获得积分20
6秒前
6秒前
顾矜应助娜尼啊采纳,获得10
7秒前
Simonn29完成签到,获得积分10
8秒前
8秒前
追寻雨完成签到 ,获得积分10
8秒前
qi完成签到,获得积分10
9秒前
10秒前
huahua完成签到,获得积分20
10秒前
小硕土川完成签到,获得积分10
10秒前
11秒前
重要问筠完成签到,获得积分10
11秒前
量子星尘发布了新的文献求助10
11秒前
xuan完成签到,获得积分10
11秒前
阳光香水应助Jay采纳,获得10
11秒前
Freya完成签到,获得积分10
11秒前
江南烟雨如笙完成签到 ,获得积分10
11秒前
Nora完成签到 ,获得积分10
12秒前
12秒前
胡豆脆脆发布了新的文献求助10
13秒前
认真飞瑶发布了新的文献求助10
13秒前
13秒前
wy.he应助112233采纳,获得10
13秒前
司徒诗蕾完成签到 ,获得积分10
13秒前
14秒前
天天快乐应助ff采纳,获得10
14秒前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
Cognitive Neuroscience: The Biology of the Mind 1000
Technical Brochure TB 814: LPIT applications in HV gas insulated switchgear 1000
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
Picture Books with Same-sex Parented Families: Unintentional Censorship 500
Nucleophilic substitution in azasydnone-modified dinitroanisoles 500
不知道标题是什么 500
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3969383
求助须知:如何正确求助?哪些是违规求助? 3514211
关于积分的说明 11172730
捐赠科研通 3249476
什么是DOI,文献DOI怎么找? 1794909
邀请新用户注册赠送积分活动 875441
科研通“疑难数据库(出版商)”最低求助积分说明 804827