生物
免疫系统
肿瘤微环境
癌变
泛素结合酶
癌症研究
下调和上调
泛素
免疫学
癌症
生物化学
泛素连接酶
基因
遗传学
作者
Siying Sun,Jun Ni,Jiamin Liu,Juofang Tan,Runsen Jin,Xiaomin He,Xuefeng Wu
标识
DOI:10.1002/eji.202451118
摘要
Tumor cell-intrinsic ubiquitin-conjugating enzyme Ubc13 promotes tumorigenesis, yet how Ubc13 in immune cell compartments regulates tumor progression remains elusive. Here, we show that myeloid-specific deletion of Ubc13 (Ubc13
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