Causal Associations between Sleep Traits, Sleep Disorders, and Glioblastoma: A Two-Sample Bidirectional Mendelian Randomization Study

Glioblastoma (GBM), a highly aggressive brain tumor predominantly affecting individuals over 40, often co-occurs with sleep disorders. However, the causal relationship remains unclear. This study employed a bidirectional Mendelian randomization (MR) approach to investigate the causal links between sleep traits/disorders and GBM.