龙胆科
黄原酮
环烯醚萜
糖苷
化学
龙胆属
生物
立体化学
传统医学
生物化学
植物
医学
作者
Hüseyin Akşit,Sefa Gözcü,Ahmet Altay
出处
期刊:Phytochemistry
[Elsevier]
日期:2022-10-27
卷期号:205: 113484-113484
被引量:9
标识
DOI:10.1016/j.phytochem.2022.113484
摘要
Centaurium erythraea Rafn. (Gentianaceae) is used in internal traditional therapy as an anthelmintic, hypotensive, antipyretic, and antidiabetic. It is used externally for the treatment of wounds. Ursolic acid, maslinic acid, secologanin, secologanin dimethyl acetal, centauroside A, erythraeaxanthone I, erythraeaxanthone II, and demethyleustomin were isolated from aerial parts of Centaurium erythraea and were identified using spectroscopic methods, including NMR and mass spectrometry. The cytotoxic potency of undescribed compounds was evaluated by the XTT assay against human breast cancer MCF-7, MDA-MB-453 and mouse fibroblast 3T3-L1 cell lines. Erythraeaxanthone II was found to have the most potent cytotoxic activity.
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