嗜酸性粒细胞
慢性阻塞性肺病
杜皮鲁玛
炎症
医学
免疫学
内科学
哮喘
作者
Surya P. Bhatt,Klaus F. Rabe,Nicola A. Hanania,Claus Vogelmeier,Mona Bafadhel,Stephanie A. Christenson,Alberto Papi,Dave Singh,Elizabeth Laws,Naimish Patel,George D. Yancopoulos,Bolanle Akinlade,Jennifer Maloney,Xin Lu,Déborah Bauer,Ashish Bansal,Raolat M. Abdulai,Lacey B. Robinson
标识
DOI:10.1056/nejmoa2401304
摘要
In patients with COPD and type 2 inflammation as indicated by elevated blood eosinophil counts, dupilumab was associated with fewer exacerbations and better lung function than placebo. (Funded by Sanofi and Regeneron Pharmaceuticals; NOTUS ClinicalTrials.gov number, NCT04456673.).
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