Functional near-infrared spectroscopy: A novel tool for detecting consciousness after acute severe brain injury

神经影像学 功能近红外光谱 意识的神经相关物 大脑活动与冥想 心理学 最小意识状态 获得性脑损伤 持续植物状态 意识 神经功能成像 认知 静息状态功能磁共振成像 感知 神经科学 感觉加工 认知心理学 感觉系统 脑电图 康复 前额叶皮质
作者
Karnig Kazazian,Androu Abdalmalak,Sergio L. Novi,Loretta Norton,Reza Moulavi-Ardakani,Matthew Kolisnyk,Teneille Gofton,Rickson C. Mesquita,Adrian M. Owen,Derek Debicki
出处
期刊:Proceedings of the National Academy of Sciences of the United States of America [Proceedings of the National Academy of Sciences]
卷期号:121 (36)
标识
DOI:10.1073/pnas.2402723121
摘要

Recent advancements in functional neuroimaging have demonstrated that some unresponsive patients in the intensive care unit retain a level of consciousness that is inconsistent with their behavioral diagnosis of awareness. Functional near-infrared spectroscopy (fNIRS) is a portable optical neuroimaging method that can be used to measure neural activity with good temporal and spatial resolution. However, the reliability of fNIRS for detecting the neural correlates of consciousness remains to be established. In a series of studies, we evaluated whether fNIRS can record sensory, perceptual, and command-driven neural processing in healthy participants and in behaviorally nonresponsive patients. At the individual healthy subject level, we demonstrate that fNIRS can detect commonly studied resting state networks, sensorimotor processing, speech-specific auditory processing, and volitional command-driven brain activity to a motor imagery task. We then tested fNIRS with three acutely brain injured patients and found that one could willfully modulate their brain activity when instructed to imagine playing a game of tennis—providing evidence of preserved consciousness despite no observable behavioral signs of awareness. The successful application of fNIRS for detecting preserved awareness among behaviorally nonresponsive patients highlights its potential as a valuable tool for uncovering hidden cognitive states in critical care settings.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
大幅提高文件上传限制,最高150M (2024-4-1)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
斯文败类应助一朵向阳花采纳,获得10
1秒前
默默绮梅完成签到,获得积分10
1秒前
Clover发布了新的文献求助10
3秒前
黄诗荏关注了科研通微信公众号
3秒前
张腾雕完成签到 ,获得积分10
4秒前
科研通AI2S应助DQ2pi采纳,获得10
4秒前
琪琪发布了新的文献求助10
7秒前
7777777发布了新的文献求助10
7秒前
Ljc发布了新的文献求助10
7秒前
zzl完成签到,获得积分10
7秒前
zzz发布了新的文献求助10
8秒前
852应助蘑菇蘑菇采纳,获得10
8秒前
DT发布了新的文献求助50
9秒前
9秒前
9秒前
Okpooko发布了新的文献求助30
10秒前
ciana完成签到 ,获得积分10
10秒前
11秒前
11秒前
guang发布了新的文献求助10
12秒前
12秒前
13秒前
无奈烤鸡发布了新的文献求助10
14秒前
烟花应助明研采纳,获得10
14秒前
sodisgel发布了新的文献求助10
14秒前
时尚的芹菜完成签到,获得积分10
17秒前
stormrat完成签到,获得积分10
17秒前
萤火虫完成签到,获得积分10
18秒前
18秒前
烟花应助乐园采纳,获得10
19秒前
酷波er应助gwh68964402gwh采纳,获得30
20秒前
大个应助Nostalgia采纳,获得10
23秒前
11完成签到,获得积分10
26秒前
放空发布了新的文献求助10
26秒前
二条完成签到,获得积分10
29秒前
29秒前
boom发布了新的文献求助10
31秒前
32秒前
Jasper应助石会发采纳,获得10
33秒前
如初发布了新的文献求助10
33秒前
高分求助中
Sustainability in ’Tides Chemistry 2000
Sustainability in ’Tides Chemistry 1500
Studien zur Ideengeschichte der Gesetzgebung 1000
The ACS Guide to Scholarly Communication 1000
TM 5-855-1(Fundamentals of protective design for conventional weapons) 1000
Handbook of the Mammals of the World – Volume 3: Primates 805
Ethnicities: Media, Health, and Coping 800
热门求助领域 (近24小时)
化学 医学 生物 材料科学 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 基因 遗传学 催化作用 物理化学 免疫学 量子力学 细胞生物学
热门帖子
关注 科研通微信公众号,转发送积分 3070883
求助须知:如何正确求助?哪些是违规求助? 2724846
关于积分的说明 7487780
捐赠科研通 2372220
什么是DOI,文献DOI怎么找? 1257893
科研通“疑难数据库(出版商)”最低求助积分说明 610135
版权声明 596891