调节器
细胞因子
溴尿嘧啶
负调节器
炎症性肠病
免疫学
炎症反应
炎症
医学
癌症研究
生物
化学
内科学
细胞生物学
生物化学
信号转导
表观遗传学
基因
疾病
作者
Eleonora Franzè,Federica Laudisi,Claudia Maresca,Antonio Di Grazia,Andrea Iannucci,Teresa Pacifico,Angela Ortenzi,Giuseppe Sica,Elisabetta Lolli,Carmine Stolfi,Ivan Monteleone,Giovanni Monteleone
标识
DOI:10.1093/ecco-jcc/jjae104
摘要
Bromodomain-containing protein 4 (BRD4), one of the components of the bromodomain and extraterminal domain (BET) family, is a transcriptional and epigenetic regulator of cellular proliferation and cytokine production. In this study, we assessed whether BRD4 regulates the cytokine response in inflammatory bowel diseases (IBD).
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