生物传感器
化学
自组装
Zeta电位
聚酯纤维
表面改性
纳米颗粒
单层
检出限
光谱学
纳米材料
化学工程
分析化学(期刊)
核化学
纳米技术
材料科学
有机化学
物理化学
色谱法
工程类
物理
量子力学
作者
Yanlian Niu,Sisheng Hu,Qian Zhou,Yang Liu,Yuhong Liu,Jing Zhao,Mimi Wan,Wenbo Zhao,Jian Shen
摘要
Self-assembly techniques have been demonstrated to be a useful approach to developing new functional nanomaterials. In this study, a novel method to fabricate a manganese phosphate self-assembly monolayer (SAM) on a hyperbranched polyester (HBPE-OH) nanoparticle surface is described. First, the second-generation aliphatic HBPE-OH was carboxy-terminated, phosphorylated, and then ionized with manganese by a three-step modification process. The final product of HBPE-AMPA-Mn2+ particles was obtained and characterised by FT-IR spectroscopy, 1H NMR spectroscopy, transmission electron microscopy (TEM), Zeta potential, and energy dispersive spectroscopy (EDS). Moreover, the HBPE-AMPA-Mn2+ particles were used to construct a novel biosensor for detection of superoxide anions (O2•−) released from HeLa cells. Results showed that the response currents of this biosensor were proportional to the O2•− concentration ranging from 0.79 to 16.6 μM, and provided an extremely low detection limit of 0.026 μM (S/N = 3). The results indicate that the particle-decorated electrode surface, which involved a hyperbranched structure and a surface self-assembly technology, proposed here will offer the ideal catalytic system for electrochemical enzymatic sensors.
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