极光激酶
极光抑制剂
极光激酶B
极光A激酶
胞质分裂
激酶
有丝分裂
癌症研究
染色体不稳定性
中心体
细胞周期
癌症
生物
生物信息学
细胞生物学
细胞
遗传学
细胞分裂
染色体
基因
作者
Chun Hei Antonio Cheung,Sailu Sarvagalla,Jane Ying-Chieh Lee,Yi-Chun Huang,Mohane Selvaraj Coumar
标识
DOI:10.1517/13543776.2014.931374
摘要
Introduction: Aurora kinase A, B and C, members of serine/threonine kinase family, are key regulators of mitosis. As Aurora kinases are overexpressed in many of the human cancers, small-molecule inhibitors of Aurora kinase have emerged as a possible treatment option for cancer.
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