Synthesis and Characterization of DAM-1 type Materials

ABSTRACT Vitamin E-TPGS (α-tocopheryl polyethylene glycol 1000 succinate) was found to be an effective template for the preparation of a novel hexagonal mesoporous silica referred to as DAM-1 (Dallas Amorphous Material-1). Depending upon the temperature and gel composition various morphologies can be achieved, including spheres, gyroids, discoids, hexagonal plates and rods. Characterization of these composites as well as a preliminary evaluation of DAM-1 as a drug delivery system under physiological conditions is also presented.