光催化
表面改性
化学选择性
炔基化
化学
氢原子
氢键
基质(水族馆)
组合化学
催化作用
光化学
立体化学
分子
光催化
有机化学
烷基
物理化学
地质学
海洋学
作者
Satobhisha Mukherjee,R. Aleyda Garza‐Sanchez,Adrián Tlahuext-Aca,Frank Glorius
标识
DOI:10.1002/anie.201708037
摘要
Abstract The development of new hydrogen‐atom transfer (HAT) strategies within the framework of photoredox catalysis is highly appealing for its power to activate a desired C−H bond in the substrate leading to its selective functionalization. Reported here is the first photoredox‐mediated hydrogen‐atom transfer method for the efficient synthesis of ynones, ynamides, and ynoates with high regio‐ and chemoselectivity by direct functionalization of C (O)−H bonds. The broad synthetic application of this method has been demonstrated by the selective functionalization of C(O)−H bonds within complex molecular scaffolds.
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